THALASSEMIA N ME

Subtitle

Blog

LEUKEMIA VS THALASSEMIA

Posted by Goh Chun Hui on July 15, 2013 at 4:20 AM

 


What is Leukemia ?


 

Leukemia is a cancer of the bone marrow and other blood forming organs. It involves the multiplication of immature white cells at the expense of blood elements.

 

 

What is Thalassemia ?


 

Thalassemia is an inherited blood disorder which is caused by an abnormal gene. A person with Thalassemia is unable to produce normal hemoglobin in the blood.


 

What are the causes of Leukemia ?


 

As for most other cancers, the majority of the leukemia is of unknown cause. However, certain conditions are known to cause leukemia; these include exposure to radiation, chemicals, inherited conditions such as Down syndrome etc.


 

What are the causes of Thalassemia ?


 

Thalassemia is an inherited blood disorder which is caused by an abnormal/missing gene. A person with Thalassemia is unable to produce normal functioning hemoglobin in the blood.


 

What are the symptoms of Leukemia ?



The symptoms can be vague and non-specific. However, most patients present with the one of the following symptoms. Fatigue, breathlessness on exertion, bleeding nose or gum, easy bruising of skin, fever, weight loss, poor appetite etc.



What are the symptoms of Thalassemia ?


 

The symptoms vary with severity of thalassemia/anemia. The common presentations include lethargy, shortness of breath, palpitations, giddiness and pale appearance.


 

What are the different types of Leukemia ?


 

There are many types of leukemia. In general, it can be classified into acute and chronic and these can further subclassified into various types according to the cell of origin and their appearances.


 

What are the different types of Thalassemia ?


 

There are two types of Thalassemia:


 

(I) Thalassemia minor (Thalassemia trait)

 

(II) Thalassemia major.


 

A person who has inherited one Thalassaemia gene is said to have Thalassemia minor (Thalassaemia trait). He or she is healthy and leads a normal life. Most people with Thalassemia minor do not know that they have it. However, the affected persons can pass on the abnormal gene to their children.



Thalassemia major is a severe form of anemia. The affected person has inherited two Thalassemia genes, one from each parent. He or she may look normal at birth but within 1-2 years of life, will suffer from severe anemia, which leads to poor growth and development as well as a shorter lifespan.



Is Leukemia an inheritable disease ?


 

There is little evidence for genetic factors. Although there are many reports if leukemia in the same family, their significance is unknown.


 

Is Thalassemia an inheritable disease ?


 

(I) If only one parent has Thalassemia minor, the following can occur:


 

•50% chance of having a child with Thalassemia minor

 

•50% chance of having a normal child

 

•none of the couple's children will get Thalassemia major.


 

(II) If both parents have Thalassemia minor, the following can occur:


 

•25% chance of having a child with Thalassemia major

 

•50% chance of having a child with Thalassemia minor

 

•25% chance of having a normal child.


 

The chances are the same with each pregnancy, no matter how many children the couple may have.


 

How is Leukemia diagnosed ?



This usually requires several blood tests and a bone marrow biopsy.


 

How is Thalassemia diagnosed ?


 

Thalassemia screening involves a simple blood test and is available at all Polyclinics.


 

How is Leukemia treated ?


 

Leukemia is usually treated with chemotherapy (chemicals which have anti-cancer effects) The treatment course varies with different types of leukemia and also the age of the patients. In selected groups of patients and disease type, bone marrow transplant can improve cure rate.


 

How is Thalassemia treated ?


 

The treatment will usually depend on the underlying cause of Thalassemia/anemia. Blood transfusion may be required in certain situations, and can sometimes be life-saving in a severely anemia patients.


 

Can Leukemia be cured ?


 

In the past, leukemia was amoung the most difficult of cancers to cure. However, methods of treatment have greatly improved over past 10 to 20 years and more patients with leukemia, especially the younger age group, have been cured if this disease.


 

Can Thalassemia be cured ?


 

The only cure available for Thalassemia Major Patients currently is a Blood Stem Cell transplant from a donor who shares the same tissue type.

 

But unfortunately, most patients are not a suitable candidate. As they do not have a suitable sibling, a parents match or an unrelated donor to offer them the chance of life.

 

Categories: None

Post a Comment

Oops!

Oops, you forgot something.

Oops!

The words you entered did not match the given text. Please try again.

Already a member? Sign In

1 Comment

Reply joe
10:10 AM on February 28, 2017 
Thalassemia is a cancerous neoplasm in its ownright cancer of blood forming cells in the bone marrow that affect of stem cells and cells of many organs the liver and pancreas the heart, the spleen, brain, endocrine organs. Lungs, and some people also lymphatic.