|Posted by Goh Chun Hui (Jack Goh) on December 5, 2010 at 9:50 AM|
As you know Iron overload in Thalassemia Major Patients are cause by long-term regular Blood Transfusion they are having. Untreated Iron Overload progressively damages vital organs. Clinical Sequelae of Iron Overload are Cardiomyopathy, cardiac failure, Hepatic cirrhosis and Diabetes mellitus. Unbound labile plasma iron can generate toxic free radicals that cause cell death, severe tissue damage and fibrosis. So it is important to have proper chelation to reduce excess iron, the key to protecting vital organs.
That's basically for this blog post, hopefully it helps a little to let you know the danger that might cause by Iron Overload and I will see you later (: